L-Se-Methylselenoncysteine Powder
Appearance: White powder or particles
Origin: China
Stocks: in stock
Certificate: ISO,USDA, HACCP, FSSC22000,HALAL,etc.
CAS no: 26046-90-2
Application: Food, Cosmetic, Health, Pharmaceutical
- Product Description
L-Se-Methylselenoncysteine Powder – Premium Organic Selenium Supplement
Avans NutriHealth Co., Ltd. delivers pharmaceutical-grade L-Se-Methylselenoncysteine Powder as a naturally-derived organic selenium compound with superior bioavailability compared to inorganic selenium sources. Our product maintains an assay purity of ≥98.0% (HPLC tested), presented as white powder or fine granules with CAS number 26046-90-2. Manufactured under ISO, HACCP, FSSC22000, and HALAL certified facilities, this selenium ingredient originates from China with guaranteed in-stock availability. The compound demonstrates excellent thermal stability up to 180°C and water solubility of approximately 15 g/L at 25°C. Unlike selenomethionine, this methylated form provides targeted antioxidant support without non-specific protein incorporation, making it ideal for precision nutrition applications in food, cosmetic, health, and pharmaceutical formulations.

Why Choose Our Selenium Methylselenoncysteine?
Superior Bioavailability Profile
Your formulations deserve selenium sources your customers can actually uptake. Our compound is absorbed at 85-95% via active amino acid transporters, much higher than sodium selenite (50-60% absorption). This methylated structure avoids the first pass metabolism problems in the liver of other forms of selenium.
Improved Stability for Production
Processing conditions impact ingredient integrity. The powder is structurally stable after tableting, encapsulation and heat treatments at temperatures up to 180°C. No degradation problems in pelleting or baking applications that plague temperature sensitive selenium compounds.
Lower Toxicity Risk
Selenium supplementation is important as the safety margins are This organic version has a wider therapeutic window than inorganic selenium salts. The controlled release mechanism avoids sudden selenium spikes and alleviates potential toxicity concerns, while maintaining efficacy.

Product Specifications
Parameter | Specification |
Product Name | L-Se-Methylselenoncysteine; 3-(Methylseleno)-L-alanine |
CAS Number | 26046-90-2 |
Appearance | White powder or granules |
Assay (HPLC) | ≥98.0% |
Selenium Content | 39.5% - 41.5% |
Water Solubility | ~15 g/L at 25°C |
pH (1% solution) | 5.0 - 7.0 |
Loss on Drying | ≤0.5% |
Heavy Metals | ≤10 ppm |
Shelf Life | 24 months (proper storage) |
Storage Conditions | Cool, dry, ventilated area; sealed packaging |
Certifications | ISO, USDA, HACCP, FSSC22000, HALAL |
Primary Application Areas
Nutraceutical & Dietary Supplements
Create premium selenium products focusing on antioxidant, immunity and thyroid benefits. The powder mixes easily with capsules, tablets and powder blends at normal quantities of 50-200 mcg/serving. Your customers get bioactive selenium without the metallic aftertaste of inorganic forms.
Enrichment of Functional Foods
Incorporate organic selenium into protein bars, drinks and meal replacement items. And the neutral flavour and light colour of the chemical will not affect the sensory features of your product. In liquid applications it is stable through pasteurisation and homogenisation.
Cosmetic Formulations
Add to anti-aging skin care products that take use of selenium’s involvement in glutathione peroxidase systems. The powder dissolves in serum and cream cosmetic bases and supports skin protection against oxidative stress. Typical use levels are from 0.01% to 0.1% in topical preparations.
Preparations, Pharmaceutical
Use in clinical nutrition products for selenium deficiency states or for support of cancer therapy protocols. The high purity profile satisfies the requirements for pharmaceutical excipients to provide accurate API formulation in quality-sensitive applications.

Handling & Storage Guidelines
Store the powder in the original sealed package at temperatures between 15-25°C. Store containers tightly closed in a dry environment, less than 60% RH. It is a stable compound, but should not be exposed to light for prolonged periods.
Do not mix with strong oxidants or reducing agents that may compromise the stability of selenium during formulation. In dry mixing operations, the powder mixes easily with other substances. For liquid applications, dissolve in water or buffered solutions at pH 5.5-7.0 for maximum stability.
Handle with appropriate protective equipment. Organic selenium is less harmful than inorganic selenium; however, measures for handling the powder should be taken to avoid exposure to dust.


Manufacturing Excellence & Quality Assurance
We have full control over our supply chain with our integrated manufacturing company Avans (Qingdao) NutriHealth Technology Co., Ltd. The production plant employs a number of purification steps such as crystallisation and filtration to achieve a pharmaceutical grade of purity.
Every batch is subjected to strict testing procedures. We check selenium levels using ICP-MS analysis, confirm purity using HPLC and do a full heavy metal screening. L-Se-Methylselenoncysteine Powder microbial testing reveals it satisfies international safety standards with total plate counts <1,000 CFU/g.
Our quality management system is founded on Good Manufacturing Practices and real-time monitoring of manufacturing. You get Certificates of Analysis with full traceability documentation for regulatory compliance in your target markets.

FAQ
Q: What makes L-Se-Methylselenoncysteine different from selenomethionine?
A: This methylated form provides targeted selenium delivery without random incorporation into body proteins. Selenomethionine replaces methionine in proteins non-specifically, creating an uncontrolled selenium reservoir. Your formulations achieve predictable bioactivity with our compound.
Q: How does processing temperature affect the powder during manufacturing?
A: The compound maintains stability up to 180°C under typical processing conditions. However, avoid prolonged exposure above 200°C, which may trigger thermal decomposition. Standard tableting and encapsulation processes preserve full activity.
Q: Can this replace multi-selenium blends in supplement formulations?
A: Yes, for applications requiring consistent bioavailability and safety profiles. The single-form approach simplifies formulation while delivering superior absorption compared to blended inorganic-organic selenium products.
Q: What is the recommended shelf life under proper storage?
A: 24 months from manufacturing date when stored in original sealed containers under specified conditions. We provide stability data supporting this timeframe with <2% potency loss.
Q: Does the powder require special regulatory documentation?
A: We supply complete regulatory support including Certificates of Analysis, Manufacturing Authorization, and compliance documentation for FDA, EU, and other international regulatory frameworks.
Partner with Avans NutriHealth
Ready to elevate your product formulations with premium L-Se-Methylselenoncysteine Powder? Contact us today at Lillian@avansnutri.com for product samples.












